ISOLATION AND STRUCTURE ELUCIDATION OF DAIDZEIN AND GENISTEIN FROM SIRAITIA GROSVENORII

Authors

  • Venkata Sai Prakash Chaturvedula Department Organic Chemistry, The Coca-Cola Company, Global Research and Development, One Coca-Cola Plaza, Atlanta, GA 30313, USA
  • Indra Prakash Department Organic Chemistry, The Coca-Cola Company, Global Research and Development, One Coca-Cola Plaza, Atlanta, GA 30313, USA

Keywords:

Siraitia grosvenorii, Curcubitaceae, Luo Han Guo, , Isofalvones, NMR, MS

Abstract

Two isoflavones were isolated by the purification of the commercial extract of Luo Han Guo (Siraitia grosvenorii) on a C-18 column using a Biotage Flash Chromatography system. The structure of the isolated compounds were characterized as 4', 7- dihydroxyisoflavone (Daidzein) and 4',5,7,-trihydroxyisoflavone (Genistein) on the basis of extensive NMR and Mass spectral data. The complete 1H and 13C NMR spectral assignments are herewith assigned for Daidzein and Genistein on the basis of 1D ( 1H and 13C) and 2D (COSY, HSQC, HMBC) NMR and high resolution mass (HRMS) spectroscopic data.

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Published

2013-01-01

How to Cite

Chaturvedula, V. S. P., & Prakash, I. (2013). ISOLATION AND STRUCTURE ELUCIDATION OF DAIDZEIN AND GENISTEIN FROM SIRAITIA GROSVENORII. Asian Journal of Pharmaceutical Research and Development, 1(1), 67–72. Retrieved from https://www.ajprd.com/index.php/journal/article/view/14

Issue

Volume 1st Issue 1st Jan-Feb 2013

Section

Research Articles

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