Vinpocetine: Hype, Hope and Hurdles towards Neuroprotection
The in progress research studies and the current knowledge about vinpocetine strongly suggest that “the one molecule fits for many at many times” This review provides a brief overview of vinpocetine for its pharmacokinetics, pharmacodynamics, uses, adverse effects and research summary. In theory, such an ideal “Vinpocetine” preferably known as nootropic is a very effective tool used in memory enhancement. Vinpocetine is a safe and non-toxic with a marvelous range of efficient and structural benefits for superior vigour. However, considering the pharmacokinetic study and uses of Vinpocetine it is a suitable candidate to develop various dosage forms for various disorders. Vinpocetine enhances brain circulation and oxygen consumption by dilating blood vessels and reducing blood stickiness. Vinpocetine is a potent inhibitor of the voltagedependent Na+ channels and a selective inhibitor of the Ca2+/caldmoduline-dependent phosphodiesterasethere. Both vinpocetine and its main metabolite cis-apovincaminic acid exert a neuroprotective type of action. Some hurdles may be produced due to Vinpocetine in the patients associated with Hypotension, Constipation and Seizure.
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