In Vitro Test of Antibacterial Ethanol Extract, n-Hexane Fraction and Ethyl acetate Fraction of Sungkai Leaf (Peronema cenescens) Against Salmonella typhi

Authors

  • Sitepu Nadroh Br. Department of Pharmacy, Poltekkes Kemenkes Medan, Indonesia

DOI:

https://doi.org/10.22270/ajprd.v8i3.757

Keywords:

Antibacterial, Sungkai, Peronemacenescens, S. typhi.

Abstract

Object: This study aims to look at the class of compounds and the comparison of the antibacterial activity of ethanol extract, n-hexane fraction and ethyl acetate of Sungkai leaves against Salmonella typhi.

Methods: Study included phytochemical screening and in vitro antibacterial testing of ethanol extract, n-hexane fraction and ethyl acetate of Sungkai leaves against Salmonella typhi.

Results: obtained groups of chemical compounds alkaloids, flavonoids, glycosides, anthraquinones, tannins and triterpenoids/steroids on Sungkai leaf powder. Ethanol extract of Sungkai leaves obtained resistance at a concentration of 20% by 12.7 mm, and inhibition of the ethyl acetate fraction at a concentration of 20% of 14.8 mm.

Conclusion: Ethyl acetate fraction of Sungkai leaves have antibacterial properties against S. typhi which is greater than ethanol extract and hexane fraction of leaf heal.

 

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Author Biography

Sitepu Nadroh Br., Department of Pharmacy, Poltekkes Kemenkes Medan, Indonesia

Department of Pharmacy, Poltekkes Kemenkes Medan, Indonesia

References

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Published

2020-06-15

How to Cite

Br., S. N. (2020). In Vitro Test of Antibacterial Ethanol Extract, n-Hexane Fraction and Ethyl acetate Fraction of Sungkai Leaf (Peronema cenescens) Against Salmonella typhi. Asian Journal of Pharmaceutical Research and Development, 8(3), 59–61. https://doi.org/10.22270/ajprd.v8i3.757

Issue

Vol. 8 No. 3 (2020): Vol 8 No 3 (2020): Vol 8 No 3 (2020): Volume 8 Issue 3 May - June. 2020

Section

Research Articles

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