A Review on Emulgel
DOI:
https://doi.org/10.22270/ajprd.v9i4.1007Keywords:
chewable tablet, lubrication, disintegration, compressibility etc.Abstract
Chewable dosage forms for example tablets, delicate, pills, gums, chewable squares is long piece of drug specialist armamentarium. They are required to be break and bit in the middle of the teeth before administration. These tablets are given to the children who have difficulty in swallowing and to the adults who dislike swallowing. These tablets are intended to disintegrate smoothly in the mouth at a moderate rate either with or without actual chewing, characteristically chewable tablets have a smooth texture upon disintegration, are pleasant tasting and leave no bitter or unpleasant taste. Geriatric and pediatric patients and travelling patients who may not have ready access to water are most need of easy swallowing dosage forms like chewable tablets. The major formulation factors are flow, lubrication, disintegration, organoleptic properties, compressibility, compatibility and stability, which are common to regular (swallowed) and chewable tablets; however, organoleptic properties of the active drug substances are primary concern here. A formulator may use one or more approaches to arrive at a combination of formula and process that result in product with good organoleptic properties.
Downloads
References
2. Gaur PK, Mishra S, Purohit S and Dave K: Transdermal Drug Delivery System: A Review. Asian Journal of Pharmaceutical and Clinical Research, 2009.
3. Bachhav Y., Patravale V. Microemulsion based vaginal gel of fluconazole: formulation, in vitro and in-vivo evaluation. Int J Pharmaceutics, 2009; 365:175-179.
4. Baibhav J., Rana G., Vikas S. Comprehensive review on the recent advances in topical drug delivery. Int Res J Pharm, 2011; 66-70.
5. Cecv G. Preclinical characterisation of NSAIDS in ultra deformable carriers or conventional topical gels. Int J Pharm, 2008; 1520-1621.
6. Chaudhary A., Tiwari N., Jain V., Singh R. Microporous bilayer osmotic tablet for colon specific delivery. Eur J Pharmaceut Biopharmaceut, 2011; 78(1):134-140.
7. Brown, M.B, Jones, S.A. Hyaluronic acid: a unique topical vehicle for the localized delivery of drugs to the skin. JEADV. 2005; 2005(19):308-18.
8. E.C. Huskins and S. Donnelly. Hyaluronic acid in treatment of Osteoarthritis of Knee. British Society of Rheumatology 1999;38(7):602-07
9. Monica Rao, Girish Sukre, Sheetal Aghav and Mnameet kumar. Optimization of Metronidazole Emulgel. Hindwai Publishing Cooperation Journal of Pharmaceutics 2013; 2013:1-9
10. A.S. Panwar, N. Upadhyay, M. Bairagi, S. Gujar, G.N. Darhekar, D.K. Jain. Emulgel: A Review. Asian Journal of Pharmacy and Life science 2011; 1(3):333-43.
11. Vivek Chavda and Vishal Rupapara. Formulation and Evaluation of Naproxen Emulgel for topical delivery by a modified method. Int J Compr Pharm.2013; 04(07):1-4.
12. Anu Hardenia, Jayronia S, Jain S. Emulgel: An Emergent tool in topical drug d.`elivery. IJPSR 2014; 5(5): 1653-60.
13. Shailendra Kumar Sah, Badola A, Nayak BK. Emulgel: Magnifying the application of topical drug delivery. Indian Journal of Pharmaceutical and Biological Research (IJPBR) 2017; 5(1):25-33.
14. Alberto Migliore, Granata M. Intra-articular use of hyaluronic acid in the treatment of osteoarthritis. Clinical Interventions in Aging 2008; 3(2):365-69.
15. Francesco Faraldi, Papa V, Santoro D, Rasà D, Mazza AL, Rabbione MM, Russo. A New Eye Gel Containing Sodium Hyaluronate and Xanthan Gum for the Management of Post-Traumatic Corneal Abrasions, Clin Ophthalmol, 2012: 6:727-31.
Published
How to Cite
Issue
Section
AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).