The Antibiotic Resistance Crisis
DOI:
https://doi.org/10.22270/ajprd.v11i5.1321Keywords:
Antibiotic Resistant Environment. PollutionAbstract
Numerous deaths from infectious diseases have raised public awareness of their dangers, promoting global antimicrobial research. However, antibiotic demand and use, on the other hand, have increased antibiotic levels in natural ecosystems. Natural selection and adaptation induced antibiotic resistance gene mutations in bacterial populations. Dissemination of antibiotic resistance genes in ecosystems resulted in the emergence of antibiotic-resistant bacteria, leading to a variety of antibiotic-resistant diseases on a global scale. This review paper provides an overview of the antibiotic discovery history, antibiotic screening techniques, and industrial antibiotic production processes. In addition, the emergence of antibiotic-resistant microorganisms and the antibiotics’ impact on the environment have been reviewed, and suggestions were given. The ecological perspective on antibiotic resistance has also been discussed. New drug development seems to be the prime requisite now to control microbes that no longer respond to the drug.
Downloads
References
2. Gould IM, Bal AM. New antibiotic agents in the pipeline and how they can overcome microbial resistance. Virulence. 2013; 4(2):185–191.
3. Wright GD. Something new: revisiting natural products in antibiotic drug discovery. Can J Microbiol. 2014; 60(3):147–154.
4. Sengupta S, Chattopadhyay MK, Grossart HP. The multifaceted roles of antibiotics and antibiotic resistance in nature. Front Microbiol. 2013; 4:47. [PMC free article] [P
5. Centers for Disease Control and Prevention, Office of Infectious Disease Antibiotic resistance threats in the United States, 2013. Apr, 2013. Available at: Accessed January 28, 2015.
6. Congressional Research Service Report Life expectancy in the United States. Mar, 2005. Available at: Accessed January 5, 2015.
7. Spellberg B, Gilbert DN. The future of antibiotics and resistance: a tribute to a career of leadership by John Bartlett. Clin Infect Dis. 2014; 59 (suppl 2):S71–S75.
8. Viswanathan VK. Off-label abuse of antibiotics by bacteria. Gut Microbes. 2014; 5(1):3–4.
9. Read AF, Woods RJ. Antibiotic resistance management. Evol Med Public Health. 2014; 2014(1):147.
10. The antibiotic alarm. Nature. 2013; 495(7440):141.
11. Lushniak BD. Antibiotic resistance: a public health crisis. Public Health Rep. 2014; 129(4):314–316.
12. Gross M. Antibiotics in crisis. Curr Biol. 2013; 23(24):R1063–R1065.
13. Piddock LJ. The crisis of no new antibiotics—what is the way forward? Lancet Infect Dis. 2012; 12(3):249–253.
14. Bartlett JG, Gilbert DN, Spellberg B. Seven ways to preserve the miracle of antibiotics. Clin Infect Dis. 2013; 56(10):1445–1450.
15. Michael CA, Dominey-Howes D, Labbate M. The antibiotic resistance crisis: causes, consequences, and management. Front Public Health. 2014; 2:145.
16. Rossolini GM, Arena F, Pecile P, PolliniS. Update on the antibiotic resistance crisis. ClinOpinPharmacol. 2014; 18:56–60.
17. Van Boeckel TP, Gandra S, Ashok A. Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data. Lancet Infect Dis. 2014; 14(8):742–750.
18. Luyt CE, Brechot N, Trouillet JL, Chastre J. Antibiotic stewardship in the intensive care unit. Crit Care. 2014; 18(5):480.
19. Gelles D. Merck in $8.4 billion deal for Cubist, big maker of antibiotics. New York Times. Dec 8, 2014. Available at: Accessed January 5, 2015.
20. Itani KM, Shorr AF. FDA guidance for ABSSSI trials: implications for conducting and interpreting clinical trials. Clin Infect Dis. 2014; 58 (suppl 1):S4–S9.
21. Hansraj Bishnoi, Shailesh Sharma, Garvendra Singh Rathore, Omveer Singh “Wound recuperation and Approaches of Aloe Barbadensis for Traumatize Mending” Journal of Survey in Fisheries Sciences 10(4S)128-134 march 2023
22. Hansraj Bishnoi, Shailesh Sharma, Gajendra Singh Thakur, Shreyasi “A review on Moringa Olifera based On Chemical composed and Wound Healing Activities” International Journal of Education, Modern Management, Applied Science & Social Science (IJEMMASSS) 26 ISSN : 2581-9925, Impact Factor: 6.882, Volume 04, No. 03(II), July - September, 2022, pp. 26-32.
23. Hansraj Bishnoi*, Shailesh Sharma, Omveer Singh and Gajendra Singh Thakur “A Pharmacovigilance Study of Anti Hypertensive Medicines at a Jaipur Nims Hospital” World Journal of Pharmacy and Pharmaceutical Sciences, Volume 10, Issue 3, 1081-1089.DOI:
24. Hansraj Bishnoi, Shailesh Sharma, Omveer Singh, and Suneha Rani “Work study of Antihypertensive Drugs” Indian J.Sci.Res. 18 (2):321-326, 2019
25. Shailesh Sharma*, Gajendra Singh Thakur, Hansraj Bishnoi and Subhankar Ghoshal “Black Soil Based Shampoo” World Journal of Pharmacy and Pharmaceutical Sciences Volume 10, Issue 1, 601-610
26. Hansraj Bishnoi, Dr. Shailesh Sharma, Saloni Sharma, Nabil Sami Pathan” Pharmacogenomics of Matamorphine in type -2 Diabetes” AIJRPLS Volume 8, Issue1 (2023, JAN/FEB/MAR)
27. Hansraj Bishnoi1, Dr. Hariom Sharma2, Dr. Shailesh Sharma3, Shailendra Sharma4, Shreyasi5 “Pharmacological Properties of Lagenaria Siceraria” Journal of Community Pharmacy Practice, Vol: 03, No. 04, June-July 2023, page no 1-11
28. Hansraj Bishnoi1, Dr. Hariom Sharma2, Dr. Shailesh Sharma3, “Evaluation of the sPhytochemicals, in Vitro Antioxidant Activity, and Toxicity of Lagenaria Siceraria Seeds”, Eur. Chem. Bull. 2023, 12 (S3), 5068 –5079,
29. Jha KK, Aman Raj , Shreyasi , Bishnoi H, Raj M , Thakur V, Chronic Wound Healing: A Review of Current Management and Treatments, Asian Journal of Pharmaceutical Research and Development. 2023; 11(3):95-102.
30. Shreyasi*, Shailesh Sharma, Hansraj Bishnoi and Manmohan Sharma “Formulation and Evaluation of Herbal Lotion for Antimicrobial Activity” World Journal of Pharmacy and Pharmaceutical Sciences, Volume 11, Issue 5, 1907-1913 DOI: 10.20959/wjpps20225-22044
31. Shreyasi, Hansraj Bishnoi, Shailesh Sharma, Aman Raj, Keshav Kumar Jha “A Review on Disease and Treatment of Ebola Virus “2023 IJCRT, 2023; 11(2).
Published
How to Cite
Issue
Section
AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
.