Evaluation of Antidepressant Activity of Tricholepis Angustifolia in Experimental Animal
DOI:
https://doi.org/10.22270/ajprd.v13i4.1621Abstract
Artificial sweeteners are substances that mimic the taste of sugar but offer negligible or zero calories. Their discovery dates back to the 19th century with saccharin. With the rise in lifestyle diseases like obesity, diabetes etc, their role as sugar alternatives has become increasingly significant. Therefore, food industries use various artificial sweeteners that are used in weight loss, diet planning with no calories or low calorie contents instead of high calorie sugar. These sweeteners are used instead of sucrose to sweeten the product. In recent years, these are used in over 6000 or more products. United States Food and Drug Administration (US FDA) has approved aspartame, acesulfame-K, neotame, sodium cyclamate etc for use as per acceptable daily intake (ADI) value. This paper aims to provide a comprehensive overview about the introduction, structure, possible health benefits and concerns of artificial sweeteners.
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References
Sam S. Importance and effectiveness of herbal medicines. Journal of pharmacognosy and phytochemistry. 2019;8(2):354-7.
WHO Traditional medicine strategy: 2014-2023. Hong Kong, SAR, China: World Health Organization; 2013.
Lai PK, Roy J. "Antimicrobial and chemo preventive properties of herbs and spices". Curr. Med. Chem. 2004; 11(11):1451-60. doi:10.2174/0929867043365107. PMID 15180577
Verma S, Singh SP. Current and future status of herbal medicines. Veterinary world. 2008 Nov 1;1(11):347.
Kala CP, Dhyani PP, and Sajwan BS, “developing the medicinal plants sector in northern India: Challenges and opportunities”, Journals of Ethnobiolology, Ethnomedidicine, 2006, 2, 1–15.
Shiva M, “Natural medicines used in the traditional Chinese medical System”, Journal of Ethnopharmacology, 1997, 92, 1–21.
Prajapati ND, Purohit SS, Sharma AK, Kumar T. A handbook of medicinal plants: A complete source book. In A handbook of medicinal plants: a complete source book 2003 (pp. 554-554).
Patel JK, Patel PY. Botanical therapeutics: discovery, development and manufacture-prospects and constraints. Journal of Natural Remedies. 2007 Jan 1:19-30.
Kamboj VP, “Herbal medicine”, Journal of Current science, 2000, 78 (1), 35-38.
MED HJ. Herbs used for brain disorders. Hygeia J Drtgs. 2010 Mar;1400:2.
Jussawalla JM. Natures Materia medica, A handy Guide on prevention and treatment of Diseases by Rational Methods, Popular prakashan, Mumbai, 6th edn, 2001,268-269.
Rajani GP, Prasad KVSRG. Effect of Eclipta alba Linn on Learning and memory enhancing in rats,Indian Journal of Pharmaceutical Education and Research, 41(4), 2007, 369-370.
Lakshami Chandra Mishra. Psychiatric diseases, Scientific basis for Ayurvedic therapies, CRC Press, Nagpur, 3rd edn, 2004, 439 –50.
Wei Dai, Kunmiao Feng et al. Natural products for the treatment of stress-induced depression: Pharmacology, mechanism and traditional use. Journal of Ethnopharmacology Volume 285, 1 March 2022, 114692.
Martins ekor, the growing use of herbal medicines, issue relating to adverse reaction and challenges in monitoring safety, 10th jan 2014.
Kumar BA, Lakshman K, Velmurugan C et al. Antidepressant activity of methanolic extract of
Amaranthus spinosus. Basic and Clinical Neuroscience. 2014;5(1):11
Castagné V, Moser P et al. Behavioral assessment of antidepressant activity in rodents. Methods of Behaviour Analysis in Neuroscience. 2nd edition. 2009.
Lewinsohn PM, Solomon A, Seeley JR, Zeiss A. Clinical implications of" subthreshold" depressive symptoms. Journal of abnormal psychology. 2000 May;109(2):345.
[internet] Depression. world health organization. 13 sep 2021. https://www.who.int/news-room/fact-sheets/detail/depression
Chand SP, Arif H, Kutlenios RM. Depression (Nursing).
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. Washington, DC: APA Press, 2000.
Tondo L, Isacsson G, Baldessarini RJ. Suicidal behaviour in bipolar disorder: risk and prevention. CNS drugs. 2003 Jun; 17:491-511.
Altshuler LL, Hendrick V, Cohen LS. Course of mood and anxiety disorders during pregnancy and the postpartum period. Journal of Clinical psychiatry. 1998 Jan 1;59(2):29-33.
Rohan KJ, Lindsey KT, Roecklein KA, Lacy TJ. Cognitive-behavioral therapy, light therapy, and their combination in treating seasonal affective disorder. Journal of affective disorders. 2004 Jun 1;80(23):273-83.
Tsuang MT, Faraone SV. The genetics of mood disorders. Johns Hopkins University Press; 1990.
Ishaq H. Anxiolytic Effect of Herbal Medicine, KhamiraGaozabanAmbriJadwar Ood Salib Wala (KGJ) in Experimental Rat Models. Pakistan Journal of Pharmaceutical Sciences. 2014 Mar 1;27(2).
Rajput MS, Sinha S, Mathur V, Agrawal P. Herbal antidepressants. IJPFR. 2011;1(1):159-69.
Patten SB. Long-term medical conditions and major depression in the Canadian population. The Canadian Journal of Psychiatry. 1999 Mar;44(2):151-7.
Chapman DP, Perry GS, Strine TW. Peer reviewed: the vital link between chronic disease and depressive disorders. Preventing chronic disease. 2005 Jan;2(1).
Reynolds EH. Brain and mind: a challenge for WHO. The Lancet. 2003;361(9373):1924-.
Frank NE, Karp JF, Rush AJ, “Efficacy of Treatments for Major Depression” Psychopharmacology Bull, 1993; 29, 457-75.
https://www.nimh.nih.gov › health › topics › depression.
Williams S, Sah P, Anggono V, Lynch J, Meunier F. Action potentials and synapses. Queensland Brain Institute. Last modified November. 2017;9.
Faraz Saleem, Muhammad Owais Ismail, et al, Antidepressant Activity of Nardostachysjatamansi Extract in Animal Models of Depression, Journal of Pharmaceutical Research International, 2020; Article no. JPRI.63968
Evans-Lacko S, Aguilar-Gaxiola S, Al-Hamzawi A, et al. Socio-economic variations in the mental health treatment gap for people with anxiety, mood, and substance use disorders: results from the WHO World Mental Health (WMH) surveys. Psychol Med. 2018;48(9):1560-1571.
Grover S, Dutt A, Avasthi A. An overview of Indian research in depression. Indian journal of psychiatry. 2010 Jan;52(Suppl1): S178.
Depression. world health organization. 13 sep 2021 Depression (who.int) Murphy JM, Laird NM, Monson RR, Sobol AM, Leighton AH. A 40-year perspective on the prevalence of depression: the Stirling County Study. Archives of General Psychiatry. 2000 Mar 1;57(3):209-15.
Radden J. Is This Dame Melancholy?: Equating today's depression and past melancholia. Philosophy, Psychiatry, & Psychology. 2003;10(1):37-52.
Berrios GE. Melancholia and depression during the 19th century: a conceptual history. The British Journal of Psychiatry. 1988 Sep;153(3):298-304.
Hasler G, Drevets WC, Manji HK, Charney DS. Discovering endophenotypes for major depression. Neuropsychopharmacology. 2004 Oct;29(10):1765-81.
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