Exploring Lantana camara: A comprehensive insight into its bioactive constituents and therapeutic potential
DOI:
https://doi.org/10.22270/ajprd.v13i6.1655Abstract
Lantana camara is a common medicinal shrub that is known to have a wide composition of phytochemicals and has a wide therapeutic scope. The plant has had a traditional significance in treating respiratory disorders, skin ailments, infections, and inflammatory diseases but scientific attention has been given to it because of the existence of bioactive substances, including terpenoids, flavonoids, phenolic acids, glycosides, and essential oils. These elements lead to various pharmacological effects such as anti-inflammatory, antimicrobial, antioxidant, anticancer, analgesic, hepatoprotective and wound-healing and metabolic regulation. The present review summarizes the existing information on the botanical features, traditional applications, phytochemistry, and the biological activities that have been reported on L. camara. It also presents significant shortcomings in the prevailing literature such as phytochemical profile variability, inconsistency in the methodological approach, lantadene toxicity issues, and absence of clinical validation. The next round of research will focus on adoption of standardized extraction techniques, elaborate toxicity testing, chemotype characterization and clinical trials to confirm the therapeutic claims. On the whole, Lantana camara is a promising but under-investigated source of natural compounds that may be applied in the development of modern drugs.
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References
Chaubey S, Rastogi N, Srivastava M. Exploring the medicinal potential of Lantana camara: a comprehensive review of phytochemicals and therapeutic application. Phytochemistry Reviews. 2025 Apr 18:1-31.
Kakade RD, Lasure U, Kedare H, Bhingare P, Pokale S. Extraction, Isolation, and Purification of Bioactive Compounds from Lantana camara Leaves: A Comprehensive Review. Research Journal of Science and Technology. 2025 May 17;17(2):177-82.
Chintada V, Golla N. Exploring the therapeutic potential of bioactive compounds from plant sources. InBiotechnological Intervention in Production of Bioactive Compounds: Biosynthesis, Characterization and Applications 2025 Feb 26 (pp. 229-247). Cham: Springer Nature Switzerland.
Dervash MA, Yousuf A, Sandhu PS, Ozturk M. Lantana camara: A Paradoxical Pharmacopoeia. Lantana Camara: Ecological and Bioprospecting Perspectives. 2025 Oct 1:63-71.
Vigneshwaran C, Suganya C, Vasantharaj K, Kirubakaran D, Sarathi C. Biogenic Synthesis of Copper Nanoparticles from Lantana camara Flower Extract: Antioxidant and Anticancer Activities. Biomedical Materials & Devices. 2025 May 30:1-2.
Jayasinghe JM, Karunaratne DR. Invasive Alien Plant Lantana Camara—A Promising Antibacterial Agent for Combatting Multidrug Resistance. InTransformative Applied Research in Computing, Engineering, Science and Technology 2025 Apr 29 (pp. 244-250). CRC Press.
Arra K, Pasupula R. Exploring the Perspective of Lantana camara L. Flowers for Urolithiasis by In Vitro and In Vivo Studies. Tropical Journal of Natural Product Research. 2025 Jun 1;9(6).
Harini BP. Phytochemical Profiling, HPLC Analysis and Antioxidant Activity of Lantana camara Flower and Leaf Extracts. Pharmacognosy Research. 2025;17(3).
Ramírez J, Armijos C, Espinosa-Ortega N, Castillo LN, Vidari G. Ethnobotany, Phytochemistry, and Biological Activity of Extracts and Non-Volatile Compounds from Lantana camara L. and Semisynthetic Derivatives—An Updated Review. Molecules. 2025 Feb 12;30(4):851.
Shehzadi S, Noreen S, Imran H, Ikram A, Arshad MT, Gnedeka KT. Unveiling the Phytochemical Profile and Anti‐Cancer Potential of Lantana camara Leaf and Root Extracts Against MCF‐7, HepG2, and A549 Cancer Cell Lines. Food Science & Nutrition. 2025 Sep;13(9):e70915.
Sharma A, Dhanda A, Naveen, Aggarwal NK, Singh A, Kumar P. Evaluation of phytochemical, antimicrobial, antioxidant, antidiabetic, antigenotoxic, antimutagenic and cytotoxic potential of leaf extracts of Lantana camara. Vegetos. 2025 Jun;38(3):1218-27.
Harika B, Kumar P, Sekar I, Rajendran P, Ravi R, Baranidharan K, Ashwin NM, Prathyusha K, Thejaswini L, Ashok Kumar D. A review on phytochemistry, ethnobotany and pharmacology of Lantana camara L.
Firdaus A, Izhar SK, Qamar S, Siddiqui A, Afaq U. Phytochemical Analysis and Antimicrobial Potential of Parthenium hysterophorous and Lantana camara. Recent Patents on Biotechnology. 2025 Sep;19(3):251-9.
Harini BP. Phytochemical Profiling, HPLC Analysis and Antioxidant Activity of Lantana camara Flower and Leaf Extracts. Pharmacognosy Research. 2025;17(3).
Karunakaran S, Marimuthu P, Theivendren P, Dinakarkumar Y. Antidiabetic Potential of Lantana camara Flower Extract: Phytochemical Analysis and Enzyme Inhibition Studies. Next Research. 2025 Jun 3:100479.
Mansoori A, Singh N, Dubey SK, Thakur TK, Alkan N, Das SN, Kumar A. Phytochemical characterization and assessment of crude extracts from Lantana camara L. for antioxidant and antimicrobial activity. Frontiers in Agronomy. 2020 Nov 12;2:582268.
Shah M, Alharby HF, Hakeem KR. Lantana camara: a comprehensive review on phytochemistry, ethnopharmacology and essential oil composition. Letters in applied nanobioscience. 2020;9(3):1199-207.
Battase L, Attarde D. Phytochemical and medicinal study of Lantana camara Linn.(Verbenaceae)-A review. Asian J Pharm Clin Res. 2021;14(9):20-7.
Thorat VH, Tamboli FA, Jadhav AS, Chavan R. Phytochemical analysis and antimicrobial activity of Lantana camara. Int. J. Pharm. Chem. Anal. 2021;8:171-3.
Ramírez J, Armijos C, Espinosa-Ortega N, Castillo LN, Vidari G. Ethnobotany, Phytochemistry, and Biological Activity of Extracts and Non-Volatile Compounds from Lantana camara L. and Semisynthetic Derivatives—An Updated Review. Molecules. 2025 Feb 12;30(4):851.
Kumar S, Singh B, Yadav A. Ethanobotany and phytochemistry of Lantana camara L.(Verbenaceae). InBotanical Leads for Drug Discovery 2020 Oct 6 (pp. 389-404). Singapore: Springer Singapore.
He A, Chadha S, Kumar V. Phytocompound profiling and GC-MS analysis of Lantana camara leaf extract. Journal of the Indian Chemical Society. 2024 Nov 1;101(11):101379.
Orji EA, Ejere VC, Orji CT, Anorue CE, Ossai NI, Ojua EO, Nwani CD, Eyo JE. Phytochemical profiling and GC-MS analysis of Lantana camara leaf extract. Tropical Journal of Natural Product Research. 2024;8(7):7920-7.
Kumar R, Guleria N, Deeksha MG, Kumari N, Kumar R, Jha AK, Parmar N, Ganguly P, de Aguiar Andrade EH, Ferreira OO, de Oliveira MS. From an invasive weed to an insecticidal agent: Exploring the potential of Lantana camara in insect management strategies—A review. International Journal of Molecular Sciences. 2024 Nov 28;25(23):12788.
Ramírez J, Armijos C, Espinosa-Ortega N, Castillo LN, Vidari G. Ethnobotany, Phytochemistry, and Biological Activity of Extracts and Non-Volatile Compounds from Lantana camara L. and Semisynthetic Derivatives—An Updated Review. Molecules. 2025 Feb 12;30(4):851.
Mansoori A, Singh N, Dubey SK, Thakur TK, Alkan N, Das SN, Kumar A. Phytochemical characterization and assessment of crude extracts from Lantana camara L. for antioxidant and antimicrobial activity. Frontiers in Agronomy. 2020 Nov 12;2:582268.
Shah M, Alharby HF, Hakeem KR. Lantana camara: a comprehensive review on phytochemistry, ethnopharmacology and essential oil composition. Letters in applied nanobioscience. 2020;9(3):1199-207.
Nea F, Kambiré DA, Genva M, Tanoh EA, Wognin EL, Martin H, Brostaux Y, Tomi F, Lognay GC, Tonzibo ZF, Fauconnier ML. Composition, seasonal variation, and biological activities of Lantana camara essential oils from Côte d’Ivoire. Molecules. 2020 May 21;25(10):2400.
Thiyagarajulu N, Arumugam S. Green synthesis of reduced graphene oxide nanosheets using leaf extract of lantana camara and its in-vitro biological activities. Journal of Cluster Science. 2021 May;32(3):559-68.
Naphade V, Bhamre JS, Avaghade MM, Kale MS, Bendale AR, Borse SL, Borse LB. Phytochemical and Pharmacological Potential of Lantana Camara Linn.(2023). Int. J. Life Sci. Pharma Res. 2023;13(4):P70-80.
Thorat VH, Tamboli FA, Jadhav AS, Chavan R. Phytochemical analysis and antimicrobial activity of Lantana camara. Int. J. Pharm. Chem. Anal. 2021;8:171-3.
Mahadevaswamy M, Paniyadi SR, Lakshmikanthan A, Swamirayachar SA, Chandrashekarappa MP, Giasin K, Shivaraju VK, Chougala MB, Linul E. Plant-mediated synthesis of NiO (II) from Lantana camara flowers: a study of photo-catalytic, electrochemical, and biological activities. journal of materials research and technology. 2022 Jul 1;19:4543-56.
Dervash MA, Yousuf A, Sandhu PS, Ozturk M. Traditional Medicinal Uses and Scientific Validation of Lantana camara. InLantana Camara: Ecological and Bioprospecting Perspectives 2025 Oct 1 (pp. 53-61). Cham: Springer Nature Switzerland.
Kakade RD, Lasure U, Kedare H, Bhingare P, Pokale S. Extraction, Isolation, and Purification of Bioactive Compounds from Lantana camara Leaves: A Comprehensive Review. Research Journal of Science and Technology. 2025 May 17;17(2):177-82.
Dervash MA, Yousuf A, Sandhu PS, Ozturk M. Introduction to Lantana camara: Ecological and Bioprospecting Perspectives. InLantana Camara: Ecological and Bioprospecting Perspectives 2025 Oct 1 (pp. 1-4). Cham: Springer Nature Switzerland.
Minh TT, Huong TT, Hoang VD. Lantaeuphanosides A–E from the leaves of Vietnamese Lantana camara Linn. and their anti-inflammatory effects on RAW264. 7 macrophages. Natural Product Research. 2025 Nov 1:1-2.
Karunakaran S, Marimuthu P, Theivendren P, Dinakarkumar Y. Antidiabetic Potential of Lantana camara Flower Extract: Phytochemical Analysis and Enzyme Inhibition Studies. Next Research. 2025 Jun 3:100479.
Li H, Huang R, Chen C, Huang Y, Yan R, Wang Y, Islam M, Tian X, Zhang J. Comparative chloroplast genomics and phylogeny of Stachytarpheta jamaicensis and Lantana camara (Verbenaceae). Journal of Asia-Pacific Biodiversity. 2025 Oct 18.
Kumar R, Guleria N, Deeksha MG, Kumari N, Kumar R, Jha AK, Parmar N, Ganguly P, de Aguiar Andrade EH, Ferreira OO, de Oliveira MS. From an invasive weed to an insecticidal agent: Exploring the potential of Lantana camara in insect management strategies—A review. International Journal of Molecular Sciences. 2024 Nov 28;25(23):12788.
He A, Chadha S, Kumar V. Phytocompound profiling and GC-MS analysis of Lantana camara leaf extract. Journal of the Indian Chemical Society. 2024 Nov 1;101(11):101379.
Chitapalli GS, Kemisetti D. Exploration of Pharmacognostic and Pharmacological Actives on Lantana camara. Research and Reviews in Plant Science. 2024 Apr;4(14):118-30.
Kaushik Y, Arora P. Investigating the sustainable energy generation potential of an invasive weed: Lantana camara. Environmental Science and Pollution Research. 2024 Nov;31(54):62493-509.
Bhodiwal S, Agarwal R, Choudhary A, Rijhwani S. A weed Lantana camara L. and its potential in Medicinal field. Indian J. Applied & Pure Bio. Vol. 2025;40(1):336-44.
Dervash MA, Yousuf A, Sandhu PS, Ozturk M. Lantana camara: A Paradoxical Pharmacopoeia. Lantana Camara: Ecological and Bioprospecting Perspectives. 2025 Oct 1:63-71.
Li H, Huang R, Chen C, Huang Y, Yan R, Wang Y, Islam M, Tian X, Zhang J. Comparative chloroplast genomics and phylogeny of Stachytarpheta jamaicensis and Lantana camara (Verbenaceae). Journal of Asia-Pacific Biodiversity. 2025 Oct 18.
Stephen H, Bello B. Protective effect of lantana camara methanolic leaf extract against acetaminophen-induced liver injury in male albino rats. Pharmaceutical and Biomedical Research. 2024 Mar 10;10(2):135-46.
Arra K, Pasupula R. Exploring the Perspective of Lantana camara L. Flowers for Urolithiasis by In Vitro and In Vivo Studies. Tropical Journal of Natural Product Research. 2025 Jun 1;9(6).
Othman KB, Maaloul N, Nhidi S, Cherif MM, Idoudi S, Elfalleh W. Phytochemical profiles, in vitro antioxidants, and anti-inflammatory activities of flowers and leaves of Lantana camara L. Grown in south of Tunisia. Periodica Polytechnica Chemical Engineering. 2024 Jan 31;68(1):72-84.
Khairan K, Maulydia NB, Faddillah V, Tallei TE, Fauzi FM, Idroes R. Uncovering anti-inflammatory potential of Lantana camara Linn: Network pharmacology and in vitro studies. Narra J. 2024 Aug 12;4(2):e894.
Robosa JC, Ban QL, Cabigon KO, Saldo IJ. In vitro Anti-Inflammatory Activity of Common Lantana (Lantana camara) Leaf and Flower Extract Topical Ointments: Comparative Analysis and Sensory Profile. Asian Journal of Biological and Life Sciences. 2025 May;14(2):1-8.
Hoang TC, Nguyen MT, Nguyen TQ, Ho BT, Nguyen HT, Ngo TP, Tran HN, Bui TK. In vitro anti-leukemia, antioxidant, and anti-inflammatory properties of Lantana camara. Brazilian Journal of Biology. 2024 May 27;84:e279899.
Saeed OM. Comparative Evaluation of the Phytochemical and Morphological Analysis and Anti-Inflammatory Effect of Lantana camara on Mice Animal Model. The Iraqi Journal of Veterinary Medicine. 2024 Jun 28;48(1):73-80.
Dervash MA, Yousuf A, Sandhu PS, Ozturk M. Traditional Medicinal Uses and Scientific Validation of Lantana camara. InLantana Camara: Ecological and Bioprospecting Perspectives 2025 Oct 1 (pp. 53-61). Cham: Springer Nature Switzerland.
Ramírez J, Armijos C, Espinosa-Ortega N, Castillo LN, Vidari G. Ethnobotany, Phytochemistry, and Biological Activity of Extracts and Non-Volatile Compounds from Lantana camara L. and Semisynthetic Derivatives—An Updated Review. Molecules. 2025 Feb 12;30(4):851.
Hashim RK, Ibrahim OM. Comparative Evaluation of the Phytochemical and Morphological Analysis and Anti-Inflammatory Effect of Lantana camara on Mice Animal Model. Gas.;12:14.
Minh TT, Huong TT, Hoang VD. Lantaeuphanosides A–E from the leaves of Vietnamese Lantana camara Linn. and their anti-inflammatory effects on RAW264. 7 macrophages. Natural Product Research. 2025 Nov 1:1-2.
Djappa CE, Arfao AT, Metsopkeng CS, Alex MM, Laurent S, Henoumont C, Fouotsa H, Mkounga P, Nkengfack EA. Cultivability of Escherichia coli and Staphylococcus aureus in the presence of hydroethanolic extracts of Lantana camara stems and leaves: Importance of bioactive compounds in the cellular inhibition process. Scientific African. 2024 Dec 1;26:e02373.
Patil SP, Sahu KG, Andhale GS. Lantana camara mediated green synthesis of metallic nanoparticles: A mini review. Inorganic Chemistry Communications. 2024 Feb 1;160:111853.
Agrawal K, Gokhale M, Faraz R. Insecticidal and Antimicrobial Activity of Ethanolic Extract of Lantana camara and GC-MS Analysis. INTERNATIONAL JOURNAL OF PLANT AND ENVIRONMENT. 2024 Nov 30;10(03):69-78.
Kato-Noguchi H, Kato M. Compounds involved in the invasive characteristics of Lantana camara. Molecules. 2025 Jan 19;30(2):411.
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