A REVIEW ON ABERNATHY MALFORMATION

Authors

  • Deepak Kumar Department of Pharmacology, Kota College of Pharmacy, Kota, Rajasthan, India.
  • Saumya Shrivastava Department of Pharmacology, Kota College of Pharmacy, Kota, Rajasthan, India.
  • M. P. Khinchi Surya Pratap Singh Department of Pharmacology, Kota College of Pharmacy, Kota, Rajasthan, India.
  • Mohd. Shahid Khan Department of Pharmacology, Kota College of Pharmacy, Kota, Rajasthan, India.

Keywords:

Congenital Porto caval shunt, Encephalopathy, hepato pulmonary syndrome

Abstract

The first account of an absent portal vein and a congenital mesenteric-caval shunt was given by John Abernethy in 1793. Five new cases of congenital extra hepatic Porto caval shunts are described in this report .One end-to-side shunt with congenital absence of the portal vein (type 1 shunt). Four are side-to-side (type 2) shunts of which there have been only two previous reports. Type 1 shunts are associated with other congenital abnormalities and have only been recognized in girls. Five of these cases developed liver tumors. Type 2 shunts are rarer, and four of five have been boys. They are not usually associated with other anomalies. Encephalopathy may be associated with these shunts in adults, and surgical closure of the side-to-side shunts is therefore recommended. End-to-side shunts are not correctable but the abnormal anatomy may create a problem for hepatic transplantation, should this be necessary for associated disorders such as biliary atresia. ―The Abernethy Malformation‖ would seem to be a suitable eponym for congenital extra hepatic Porto caval shunts.

Downloads

Download data is not yet available.

Published

2017-03-01

How to Cite

Kumar, D., Shrivastava, S., Singh, M. P. K. S. P., & Khan, M. S. (2017). A REVIEW ON ABERNATHY MALFORMATION. Asian Journal of Pharmaceutical Research and Development, 5(2), 1–012. Retrieved from https://www.ajprd.com/index.php/journal/article/view/285

Issue

Volume 5 Issue 2nd Mar- Apr 2017

Section

Review Articles

AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).

Most read articles by the same author(s)

1 2 > >>