Sustained Release: Emerging Drug Delivery System
Keywords:
SRDDS, Diffusion Controlled, Extended Release, Rotating BasketAbstract
To achieve and maintain the concentration of an administered drug within therapeutically effective range, it is often necessary to take drug dosage several times and these results in a fluctuating drug levels in plasma. Sustained release dosage forms are designed to release a drug at a predetermined rate in order to maintain a constant drug concentration for a specific period of time with minimum side effects. Sustained Release is also providing promising way to decrease the side effect of drug by preventing the fluctuation of the therapeutic concentration of the drug in the body. During the last two decades there has been remarkable increase in interest in sustained release drug delivery system. This has been due to several advantages of sustained release drug delivery over conventional dosage forms like improved patient compliance due to less frequent drug administration, reduction of fluctuation in steady-state drug levels, maximum utilization of the drug, increased safety margin of potent drug, reduction in healthcare costs through improved therapy, shorter treatment period and less frequency of dosing.
Downloads
References
2. Banker GS and Anderson NR. The Theory and Practice of Industrial Pharmacy: Tablet, Lachman, (3rded) Varghese Publishing House, Bombay,1990, 293-303.
3. Brahmankar D.M. and Jaiswal S.B., Biopharmaceutics and Pharmacokinetics, (1sted) VallabhPrakashan, Delhi, 2007, 337.
4. Lachman L, Lieberman H.A., Kanig J.L., The Theory and Practice of Industrial Pharmacy:
5. Sustained Release Dosage Form, (3rded) Varghese Publication House, Bombay, 1990, 430-431.
6. Vyas S.P., KharR.K., Controlled Drug Delivery,(1sted), VallabhPrakashan, Delhi, 2008, 6
7. John C and Morten C. The Science of Dosage Form Design, Aulton: Modified release peroral dosage forms, (2nded) Churchill Livingstone. 2002:290-300.
8. Brahmankar D.M. and Jaiswal S.B., Biopharmaceutics and Pharmacokinetics: Pharmacokinetics, (2nd ed) Vallabh Prakashan, Delhi, 2009, 399-401.
9. Vyas S.P., Khar R.K., Controlled Drug Delivery,(1sted), Vallabh Prakashan, Delhi, 2008, 157-160. 10. Robinson J.R., Lee V.H.L., V.H., Controlled drug delivery: fundamentals and applications, Informa Healthcare, Volume 20, 2011, 12-36. 11. Sampathkumar K.P., Bhowmik D., Shrivastava S., Paswan S., Dutta A.S., Sustained Release Drug Delivery System Potential, The Pharma Innovation, 2012, 1(2),52-56. 12. Brahmankar D.M. and Jaiswal S.B., Biopharmaceutics and Pharmacokinetics, (1sted) VallabhPrakashan, Delhi, 2007, 342-347. 13. Popli H., Sharma S.N., 1990, "Evaluation of sustained release formulations". The Eastern
Published
How to Cite
Issue
Section
AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).