FORMULATION AND EVALUATION OF NILAVEMBU KUDINEERCAPSULES
DOI:
https://doi.org/10.22270/ajprd.v7i1.468Keywords:
Nilavembu Kudineer churnam, ethanol, biomolecule, angle of repose,bulk density and microbial test.Abstract
The herbal medicine Nilavembu Kudineer is very effective in viral fevers. The study was effort to prepare a Nilavembu Kudineerherbal capsule from Nilavembu Kudineer churnam. The task of this work is, to detainment of active biomolecules and ensure their biological activity. The Nilavembu Kudineerchurnamwas extracted by ethanol and water solvents, then the extract was dried. The resultant dried extract powder was screened by various chemical and microbiological tests for to ensure the potency. The results confirms that both the extract haveactive biomolecules and possess their activity. Based on the microbiological activity NVK water extract was comparatively better than the ethanol using extract powder. The dried NVK water extract powder capsules complies with standards of capsule pre and post filling parameters such as angle of repose, bulk density, tapped density, carr’s index and hausner’s ratio. The filled NVK capsule complies the post filling evaluations of weight variation, disintegration. In future stability, dosage titrations and more number of microbial test need to conduct for their effectiveness of the formulation.
Downloads
References
2. Harihara Mahadevan et al., Literature Review on Siddha Herbal Formulations (Kudineer) Available for the Management of Dengue - International Journal of Pharmacology and Clinical Sciences 2016; 5(3): 90-96.
3. Thilak Kumar R et al., FTIR analysis on nilavembu kudineer churanam and acetominaphen- J. Chem. Pharm. Res., 2016;8(3):634-639.
4. Balakrishnan C et al., Pharmacognosy and chromatographic analysis of nilavembu chooranam and nilavembu tablet, a siddha polyherbal formulation - Int J Pharm Bio Sci 2013;4(2):180-186.
5. Padmini E et al., Preliminary phytochemical screening of selectedmedicinal plants of polyherbal formulation - Journal of Pharmacognosy and Phytochemistry 2016; 5(5): 277-282.
6. Jagdev singh Nilavembu kudineer (Nilavembu kashayam). Ayurtimes.com jul.2017.
7. Padmalochana K et al.,Phytochemical analysis and antimicrobial activity of king of bitter andrographis paniculata against pathogenic microbes - International Journal of Institutional Pharmacy and Life Sciences 2014; 4(6):135-142
8. Thirupathi et al., Int J Pharm Pharm Sci, 2013; 5(3):340-348.
9. Azwanida NN A Review on the Extraction Methods Use in Medicinal Plants, Principle, Strength and Limitation. Med Aromat Plants 2015; 4: (1) 196.
10. Kuppusamy mudhaliyar K N et al.,Siddha vaidhiya thirattu, Indian medicine homeopathy, Chennai, 2009; 1 (1)294.
Published
How to Cite
Issue
Section
AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).