ANTIMICROBIAL ACTIVITY AND PHYTOCHEMICAL PROPERTIES OF ACTINODAPHNE GLOMERATA LEAVES EXTRACT

Authors

  • Suharyani Ine STIKES Muhammadiyah Kuningan, Jl. Raya Cigugur-Cirendang No.D4 Rt. 09 Rw. 03 Blok Cisumur Kelurahan Cipari Kabupaten Kuningan, Jawa Barat, Indonesia
  • Harlinda Kuspradini Faculty of Forestry, Mulawarman University, Jl Ki Hajar Dewantara Kampus Gunung    Kelua, Samarinda, East Kalimantan, 75116, Indonesia
  • Julinda Manalu Faculty of Forestry, Mulawarman University, Jl Ki Hajar Dewantara Kampus Gunung    Kelua, Samarinda, East Kalimantan, 75116, Indonesia

DOI:

https://doi.org/10.22270/ajprd.v7i1.472

Keywords:

Actinodaphne glomerata, n-hexane extract, Phytochemical, Antimicrobial.

Abstract

This study aimed to determine the antimicrobial activity and chemical compounds by phytochemical analysis of Actinodaphne glomerata leaves. The extraction was performed by maceration method using n-hexane solvent. The antimicrobial activity was tested by agar diffusion method against Candida albicans, Staphylococcus aureus, Streptococcus mutans and Streptococcus sobrinus. The n-hexane crude extracts was tested for its antimicrobial activity using 125, 250 and 500 μg/well of concentrations. Based on phytochemical analysis, it showed that n-hexane extract of A. glomerata leaves contained alkaloids, triterpenoid and carbohydrates. The extract inhibited all tested microorganisms and the best inhibition zone was shown against S. sobrinus (19.56 mm) at concentration 500 μg/well.

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Author Biographies

Suharyani Ine, STIKES Muhammadiyah Kuningan, Jl. Raya Cigugur-Cirendang No.D4 Rt. 09 Rw. 03 Blok Cisumur Kelurahan Cipari Kabupaten Kuningan, Jawa Barat, Indonesia

STIKES Muhammadiyah Kuningan, Jl. Raya Cigugur-Cirendang No.D4 Rt. 09 Rw. 03 Blok Cisumur Kelurahan Cipari Kabupaten Kuningan, Jawa Barat, Indonesia

Harlinda Kuspradini, Faculty of Forestry, Mulawarman University, Jl Ki Hajar Dewantara Kampus Gunung    Kelua, Samarinda, East Kalimantan, 75116, Indonesia

Faculty of Forestry, Mulawarman University, Jl Ki Hajar Dewantara Kampus Gunung    Kelua, Samarinda, East Kalimantan, 75116, Indonesia

Julinda Manalu, Faculty of Forestry, Mulawarman University, Jl Ki Hajar Dewantara Kampus Gunung    Kelua, Samarinda, East Kalimantan, 75116, Indonesia

Faculty of Forestry, Mulawarman University, Jl Ki Hajar Dewantara Kampus Gunung    Kelua, Samarinda, East Kalimantan, 75116, Indonesia

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Published

2019-02-15

How to Cite

Ine, S., Kuspradini, H., & Manalu, J. (2019). ANTIMICROBIAL ACTIVITY AND PHYTOCHEMICAL PROPERTIES OF ACTINODAPHNE GLOMERATA LEAVES EXTRACT. Asian Journal of Pharmaceutical Research and Development, 7(1), 24–26. https://doi.org/10.22270/ajprd.v7i1.472

Issue

Vol. 7 No. 1 (2019): Volume 7 Issue 1 January- February 2019

Section

Research Articles

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