Pharmacological evaluation of Chloroxylonswietenia DC bark extract on alloxan induced Diabetic nephropathy in Wistar rats

Authors

  • Manpreet Kaur Dept. of pharmacy, SBS polytechnic and pharmacy collage Patti Tarn Taran, Punjab
  • Amit Sharma Dept. of Pharmacy Manav Bharti University, Village-Laddo, Sultanpur, Kumarhatti, District Solan, Himachal Pradesh
  • Madan Kaushik Supervisor & Head Department of Pharmacology, CT Institute of Pharmaceutical Sciences, Jalandhar-Punjab, India

DOI:

https://doi.org/10.22270/ajprd.v7i2.476

Keywords:

Diabetes, wistar rats, alloxan, nephropathy, UV Spectrophotometer, Glucose

Abstract

Diabetes is now a days consider as common problem with serious issues. Diabetes cause various other dysfunctions and issues in various organs and parts of bodies, so it should be cured and treated. Chloroxylonswietenia DC bark extract proved to be helpful in treating diabetic problems. It is highly available and can cure various other problems caused by diabetes in bodies. In present study we have studied various properties, functions, effects, of extracts of Chloroxylonswietenia DC bark extracton alloxan induced Diabetic nephropathy in Wistar rats.

Downloads

Download data is not yet available.

Author Biographies

Manpreet Kaur, Dept. of pharmacy, SBS polytechnic and pharmacy collage Patti Tarn Taran, Punjab

Asst. Professor Dept. of pharmacy, SBS polytechnic and pharmacy collage Patti Tarn Taran, Punjab

Amit Sharma, Dept. of Pharmacy Manav Bharti University, Village-Laddo, Sultanpur, Kumarhatti, District Solan, Himachal Pradesh

Asst. Professor Dept. of Pharmacy Manav Bharti University, Village-Laddo, Sultanpur, Kumarhatti, District Solan, Himachal Pradesh

References

1. B. Manash, L. Mangala, A. Sahabudin, C. Liakat, K. Saurabh. Small molecule inhibiting nuclear factor-kB Ameliorates oxidative stress and supresses renal inflammation in early stage of alloxan induced diabetic nephropathy in rats. Journal of Basic & Clinical Pharmacology. 2017;120(5):442-449.
2. G. Douglas, B. Anthony, T. Robort. Diabetic nephropathy in a sibling and albuminuria predict early GFR decline: a prospective cohort study. Journal of Bio Med central Nephrology. 2013;14(10):124-150.
3. K. Alsaad, A. Herzenberg. Distinguishing diabetic nephropathy from other causes of glomerulosclerosis: an update. Journal of Clinical Pathology. 2007; 60(1): 18–26.
4. Z. Themis, G. Fernado, B. Amely. Diabetology and Metabolic Syndrome. Bio Med Central. 2009;12(8):1-10.
5. Kumar D, Sharma A, Garg R, Asst. Prof. FORMULATION AND EVALUATION OF SUBLINGUAL TABLET OF LOSARTAN POTASSIUM. Asian Journal of Pharmaceutical Research and Development. 2018; 6(4): 54-66.
6. Sujeet Kumar, Shubham, Amit Sharma, NeelamPainuly. NIPAH VIRUS – THREAD TO PREGNANCY. Asian Journal of Pharmaceutical Research and Development. 2018; 6(5): 66-70.
7. M. Sharanabasappa, M. Jayaraj. Pharmacognostic and phytochemical investigation on stem bark of ChloroxylonSwietenia DC. An Ethnomedicinally important medicinal tree. International journal of Pharmaceutical sciences and Research. 2015;6(2):825-829.
8. P. Deepak, U. Amit. Diabetic nephropathy: Progression and Pathophysiology. Internation Journal of Medical sciences and public Health. 2012;1(2):59-70.
9. A. Atul, A. Sahil, Y. Harlokesh. Pathogenesis of diabetic nephropathy. International Journal of Pharmacy and Pharmaceutical Sciences. 2010;2(4):75-91.
10. T. Mahid. Diabetic nephropathy and antioxidants. Journal of Medical Sciences and Public Health. 2013;2(1):20-27

Published

2019-04-15

How to Cite

Kaur, M., Sharma, A., & Kaushik, M. (2019). Pharmacological evaluation of Chloroxylonswietenia DC bark extract on alloxan induced Diabetic nephropathy in Wistar rats. Asian Journal of Pharmaceutical Research and Development, 7(2), 15–22. https://doi.org/10.22270/ajprd.v7i2.476

Issue

Vol. 7 No. 2 (2019): Volume 7 Issue 2 March - April 2019

Section

Research Articles

AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).

Most read articles by the same author(s)