PHARMACOLOGY EFFECT OF CARDIOVASCULAR DRUGS ON THE LEVEL OF THYROID HORMONES AND VITAMIN-D.

Authors

  • Neelam Painuly Department of Pharmacy, Manav Bharti University, Solan, Himachal Pradesh India
  • Amit Sharma Department of Pharmacy, Manav Bharti University, Solan, Himachal Pradesh India

DOI:

https://doi.org/10.22270/ajprd.v6i4.382

Keywords:

Arrhythmia, cardiovascular, vitamin D, Amlodipine, Propranolol, Captopril, Amiodarone

Abstract

Cardiovascular system is an important system of body. This consists the heart and blood vessels. Any kind of heart disease is dangerous. Thyroid hormone is one of the leading hormones which is involving in the cardiovascular mechanism. Any disturbance in the balance of hormone can cause serious problems which may be dangerous to cardiovascular system. So it balance should be maintained properly.  Various treatment related to this are found but they may cause various alteration in the production of thyroid hormone. So in order to give proper treatment to patient all the aspects should be checked and observed properly considering the health of patient. Amlodipine, Propranolol, Captopril, Amiodarone are some of the medicines used in the treatment of these diseases. Knowledge of drug should be proper so that any risk of thyroid abnormalities can be minimized and diagnosed in proper time.

Key words: Arrhythmia, cardiovascular, vitamin D, Amlodipine, Propranolol, Captopril, Amiodarone

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References

1. George J, Joshi SR, Drugs and Thyroid, Department of Endocrinology, Seth G.S. Medical collage and Kem
hospital, Mumbai. 2007; 55: 215-223.
2. Vorperian VR, Havighurst TC, Miller S, January CT. Adverse effects of low dose amiodarone; a meta-analysis.J Am coll cardiol. 30: 791-8, 1997.
3. Murchison LE, How J, Bewsher PD. Comparison of propranolol and metoprolol in the management of
Hyperthyroidism. Br J clin pharmacol. 1979; 8: 581-87.
4. Kristensen BO, Weeke J. Propranolol-induced increments in total and free serum thyroxine in patient with essential hypertension. Clin Pharmacol Ther. 1977; 22: 864-7.
5. Sharma A, Arora P, anti-cancer activity of Cedrus depdara in 1,2- dimethyl hydrazine (DMH) induced anti-cancer model in rats. Asian Journal of Pharmaceutical Research and Development. 2018; 6(2): 70-74
6. Meier CA, Burger AC. Effects of drugs and other substances on thyroid hormone synthesis and metabolism. In Braverman LE, Utiger RD ed. Werner and IngbarÊs the thyroid: a fundamental and clinical text. Lippincott Williams and Wilkins. 2005; 22-46.
7. Basaria S, Cooper DS. Amiodarone and the thyroid. The American J Medicine. 2005; 118: 706-14.
8. Zittermann A, Schleithoff SS, Koerfer R. Putting cardiovascular disease and vitamin D insufficiency into perspective. Br J Nutr. 2005; 94: 483-92.
9. Aggarwal N, Reis JP, Michos ED. Vitamin D deficiency and its implications on cardiovascular disease. Curr Cardio Risk Rep. 2010; 4: 68-7.
10. McGreevy C, and Williams D, New Insights about Vitamin D and Cardiovascular Disease, Ann Intern Med.2011; 155:820-826.
11. Zhou C, Assem M, Tay JC, Watkins PB, Blumberg B, Schuetz EG, et al. Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug- induced osteomalacia. J Clin Invest. 2006; 16: 1703-12.
12. Van Den Bout-Van Den Beukel CJ, Fievez L, Michels M, Sweep FC, Hermus AR, Bosch ME, et al. Vitamin D deficiency among HIV type 1-infected individuals in the Netherlands: effects of antiretroviral therapy. AIDS Res Hum Retroviruses. 2008; 24:1375-82.
13. Holick MF. Vitamin D deficiency. New England Journal of Medicine. 2007; 357:266-281.
14. Pierrot-Deseilligny C. Clinical implications of a possible role of vitamin D in multiple sclerosis. Journal of Neurology. 2009; 256:1468-1479.
15. National Institute for Health and Clinical Experience. Antenatal care: routine care for the health pregnant woman. 2008; 62.
16. Sharma A, Arora Pankaj, Anti fertility activity of hydro alcoholic extract of Trillium Govanianum in ethinyl estradiol induced anti-fertility model in rats. Asian Journal of Pharmaceutical Research and Development. 2018; 6 (2): 62-69.

Published

2018-08-23

How to Cite

Painuly, N., & Sharma, A. (2018). PHARMACOLOGY EFFECT OF CARDIOVASCULAR DRUGS ON THE LEVEL OF THYROID HORMONES AND VITAMIN-D. Asian Journal of Pharmaceutical Research and Development, 6(4), 30–34. https://doi.org/10.22270/ajprd.v6i4.382

Issue

Vol. 6 No. 4 (2018): VOLUME 6 ISSUE 4 JULY - AUGUST 2018

Section

Research Articles

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